About akorn codeine
About akorn codeine
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Anaphylaxis: Anaphylaxis is reported with codeine, one of several elements in promethazine HCl and codeine phosphate oral solution.
Enhanced pressure inside your head (elevated intracranial tension). Prevent the usage of Promethazine Hydrochloride and Codeine Phosphate Oral Remedy For those who have a head injury or have been explained to that you've changes while in the tissue of one's brain (brain lesions) or improved pressure as part of your head.
Respiration problems (respiratory melancholy) that may result in Demise and opioid withdrawal can come about if You begin getting or end using other medicines although using Promethazine Hydrochloride and Codeine Phosphate Oral Solution, together with:
Codeine is understood to generally be significantly excreted with the kidney, and the risk of adverse reactions to this drug may be greater in people with impaired renal operate.
are breastfeeding or plan to breastfeed. Codeine Phosphate passes into your breast milk and will harm your newborn. You and your healthcare company need to discuss whether it is best to get Promethazine with Codeine Oral Answer or breastfeed. You should not do equally.
Simply because these reactions may be documented voluntarily from the inhabitants of unsure sizing, It's not at all always attainable to reliably estimate their frequency or create a causal marriage to drug exposure.
In some youngsters and Grown ups this occurs very quickly, and might cause you to halt respiratory and bring about Dying because of an overdose.
five.8 Pursuits Necessitating Mental Alertness: Risks of Driving or Operating Equipment Codeine and promethazine, two of the active substances in promethazine HCl and codeine phosphate oral Remedy, may well develop marked drowsiness and impair the psychological and/or physical skills needed with the performance of probably dangerous tasks such as driving a vehicle or working equipment.
Promethazine HCl and codeine phosphate oral Resolution is website not really suggested for use in Expecting Gals [see Use in Unique Populations (8.1)]. Prolonged use of promethazine HCl and codeine phosphate oral Resolution all through pregnancy may end up in neonatal opioid withdrawal syndrome, which can be lifestyle-threatening Otherwise acknowledged and dealt with, and necessitates management In line with protocols produced by neonatology industry experts.
Propulsive peristaltic waves inside the colon are diminished, though tone could possibly be increased to The purpose of spasm causing constipation. Other opioid-induced consequences may consist of a reduction in biliary and pancreatic secretions, spasm of sphincter of Oddi, and transient elevations in serum amylase.
Drug interactions, including an elevated incidence of extrapyramidal consequences, are actually claimed when some MAOI and phenothiazines are made use of concomitantly.
It's soluble in drinking water and freely soluble in Liquor. The molecular body weight is 320.88. Its molecular formula is C17H20N2S•HCl, and it has the following chemical structure.
“If any person has any Akorn items in the home, contact your pharmacy without delay and stick to up using your prescriber,” Kann explained.
e., multiple copies from the gene for cytochrome P450 isoenzyme 2D6 or substantial morphine concentrations). Small children with slumber apnea may be specifically sensitive towards the respiratory depressant outcomes of codeine.